DNA Methylation Patterns Linked to Chemotherapy Resistance in Aggressive Ovarian Cancer
Scientists have identified distinct DNA methylation patterns that distinguish chemotherapy-resistant from sensitive ovarian cancer cells. These epigenetic markers reportedly correlate with significantly worse patient survival, offering potential biomarkers for treatment response prediction. The findings could pave the way for new diagnostic approaches in managing this aggressive cancer type.
Epigenetic Markers Predict Treatment Response
Researchers have uncovered specific DNA methylation signatures associated with chemotherapy resistance in high-grade serous ovarian cancer (HGSC), according to a recent study published in Scientific Reports. The comprehensive methylome analysis reportedly identifies epigenetic patterns that distinguish chemoresistant from chemosensitive cancer cells, with significant implications for patient prognosis and treatment strategies.