Tag: Gene knockout

AIScienceTechnology

CRISPR Screen Reveals Key microRNA Driving Prostate Cancer Survival

A comprehensive CRISPR screening approach has uncovered microRNA-483-3p as a critical survival factor in prostate cancer cells. The findings reveal a previously unknown signaling network that controls programmed cell death, potentially explaining why some tumors resist conventional treatments. The discovery points toward new combination therapy strategies for advanced prostate cancer.

Breakthrough in Prostate Cancer Research

Scientists have identified a specific microRNA that appears to play a surprisingly central role in keeping prostate cancer cells alive, according to recent research findings. Using advanced CRISPR screening technology, researchers discovered that microRNA-483-3p functions as a master regulator of apoptosis—the programmed cell death process that typically eliminates damaged cells.

by Jessica Moore P.E.
InnovationScienceTechnology

Malaria Parasite’s Essential Trafficking Protein Reveals New Drug Target Potential

Researchers have characterized a previously unknown essential protein in malaria parasites that appears critical for cellular transport mechanisms. The discovery of PfPX2’s binding capabilities and localization patterns opens new avenues for understanding parasite biology and potential therapeutic interventions.

Breakthrough in Understanding Malaria Parasite Biology

Scientists have identified a previously uncharacterized protein essential for the survival of Plasmodium falciparum, the deadliest malaria parasite, according to recent research published in Scientific Reports. The protein, named PfPX2, appears crucial for the parasite’s in vitro asexual growth and may play a key role in cellular transport mechanisms between critical organelles.

by Jessica Moore P.E.