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Scientists Develop Self-Regulating Chiral Droplets with Built-In Catalytic Timers

Researchers have engineered catalytic coacervate droplets that autonomously form, create chiral microenvironments, and dissolve through built-in hydrolysis. These dynamic systems demonstrate unprecedented control over phase separation and enantioselective catalysis, offering insights into prebiotic chemistry and cellular organization.

Breakthrough in Dynamic Molecular Condensates

Scientists have developed a novel system of catalytic coacervate droplets that spontaneously form, create chiral environments, and subsequently dissolve through their own intrinsic catalytic activity, according to research published in Nature Communications. These self-regulating droplets represent one of the first examples of small molecule-based liquid-liquid phase separation systems that operate out of equilibrium through native catalytic potential, sources indicate.