RNA Structural Motifs Exhibit Unprecedented Diversity in Global Study
Researchers have identified remarkable diversity in RNA structural motifs through exhaustive analysis of nucleic acid 3D structures. The study reveals how these fundamental building blocks adapt to various biological contexts, from riboswitches to viral RNAs.
Widespread Presence of RNA Structural Elements Documented
Scientific reports indicate that GNRA tetraloop motifs, fundamental structural elements in RNA, exhibit far greater diversity than previously recognized. According to a comprehensive study published in Scientific Reports, researchers have identified 23,283 non-redundant instances of these motifs across 3,122 protein data bank entries, representing 13,729 structurally unique configurations.